SUMMARY THIAB EXPLANATION THEM NYIAJ
Tus kab mob Zika (Zika): feem ntau kis tau los ntawm kev yoov tshaj cum Aedes, niam thiab menyuam, kev hloov ntshav thiab kev sib deev.Vim tias tsis muaj tshuaj tiv thaiv tam sim no, tib neeg feem ntau kis tau tus kab mob.IgG / IgM tshuaj tiv thaiv yog tsim tawm ib lub lis piam tom qab pib, yog li kev tshawb pom ntawm IgG / IgM yog qhov tseem ceeb heev rau thaum ntxov.
Kev kuaj mob Zika.Zika tau kuaj pom raws li kev soj ntsuam serological thiab kev cais tus kab mob hauv nas lossis kab lis kev cai.Ib qho IgM immunoassay yog txoj kev kuaj pom zoo tshaj plaws.Lub zika IgM / IgG Rapid Test siv cov antigens recombinant muab los ntawm nws cov qauv protein, nws kuaj pom IgM / IgG anti-zika hauv cov neeg mob ntshav lossis ntshav hauv 15 feeb.Qhov kev xeem tuaj yeem ua tau los ntawm cov neeg ua haujlwm tsis muaj kev cob qhia lossis cov neeg ua haujlwm tsawg, yam tsis muaj cov cuab yeej kuaj sim.
PRINCIPLE
Zika IgM / IgG Rapid Test yog lateral flow chromatographic immunoassay.Cov ntawv xeem muaj xws li: 1) ib lub burgundy coloured conjugate ncoo uas muaj recombinant antigen conjugated nrog colloid kub (Zika conjugates) thiab luav IgG-kub conjugates, 2) nitrocellulose membrane strips muaj ob lub xeem bands (M thiab G bands) thiab kev tswj band (C band).M band yog pre-coated nrog monoclonal anti-tib neeg IgM rau kev tshawb pom ntawm IgM anti-Zika, G band yog pre-coated nrog reagents rau nrhiav tau ntawm IgG anti-Zika, thiab C band yog pre-coated nrog tshis los tiv thaiv. qub IgG.
Thaum lub ntim ntim txaus ntawm cov qauv kuaj tau muab xa mus rau hauv cov qauv zoo ntawm cov ntawv xeem, cov qauv txav los ntawm kev ua haujlwm capillary thoob plaws lub cassette.Anti-Zika IgM yog muaj nyob rau hauv cov qauv yuav khi rau Zika conjugates.Lub immunocomplex yog tom qab ntawd ntes tau ntawm daim nyias nyias los ntawm cov txheej txheem ua ntej-coated anti-tib neeg IgM cov tshuaj tiv thaiv, tsim cov xim burgundy M band, qhia txog Zika IgM qhov txiaj ntsig zoo.
Anti-Zika IgG yog muaj nyob rau hauv cov qauv yuav khi rau Zika conjugates.Lub immunocomplex yog ces ntes tau los ntawm pre-coated reagents ntawm daim nyias nyias, tsim ib tug burgundy xim G band, qhia ib tug Zika IgG zoo xeem.Tsis muaj ib qho kev xeem qhab nia (M thiab G) qhia tias qhov tshwm sim tsis zoo.Qhov kev ntsuam xyuas muaj kev tswj hwm sab hauv (C band) uas yuav tsum tau nthuav tawm cov xim burgundy ntawm cov tshuaj tiv thaiv kab mob ntawm tshis anti luav IgG / luav IgG-kub conjugate tsis hais txog xim kev loj hlob ntawm ib qho ntawm cov qhab nia xeem.Txwv tsis pub, cov txiaj ntsig kev xeem tsis raug cai thiab cov qauv yuav tsum tau rov kuaj dua nrog lwm lub cuab yeej.
