Rota Virus Antigen Test

Kev mob raws plab yog ib qho ntawm cov hauv paus ntsiab lus ua rau kev mob me nyuam yaus thiab kev tuag thoob ntiaj teb, ua rau 2.5 lab tus neeg tuag txhua xyoo.Tus kab mob rotavirus yog qhov ua rau mob plab hnyav hauv cov menyuam mos thiab cov menyuam yaus hnub nyoog qis dua 5 xyoos, suav txog 40% -60% ntawm mob plab hnyuv thiab ua rau kwv yees li 500,000 tus menyuam yaus tuag txhua xyoo.Thaum muaj hnub nyoog tsib xyoos, yuav luag txhua tus menyuam hauv ntiaj teb tau kis tus kabmob rotavirus tsawg kawg ib zaug.Nrog rau cov kab mob tom ntej, qhov dav dav, heterotypic antibody teb yog elicited;yog li ntawd, cov neeg laus tsis tshua muaj kev cuam tshuam.Txog niaj hnub no xya pawg ntawm rotaviruses (pab pawg AG) tau raug cais tawm thiab muaj tus yam ntxwv.Pawg A rotavirus, feem ntau rotavirus, ua rau ntau tshaj 90% ntawm tag nrho cov kab mob Rotavirus hauv tib neeg.Rotavirus feem ntau kis tau los ntawm qhov ncauj qhov ncauj, ncaj qha los ntawm ib tus neeg mus rau lwm tus.Tus kab mob titers hauv cov quav mus txog qhov siab tshaj plaws sai tom qab pib mob, ces poob qis.Lub sijhawm incubation ntawm tus kab mob rotavirus feem ntau yog ib mus rau peb hnub thiab nws tau ua raws li gastroenteritis nrog lub sijhawm nruab nrab ntawm peb mus rau xya hnub.Cov tsos mob ntawm tus kab mob muaj xws li mob me, dej raws plab mus rau mob raws plab nrog kub taub hau thiab ntuav.Kev kuaj mob ntawm tus kab mob rotavirus tuaj yeem ua tau tom qab kuaj mob gastroenteritis vim qhov ua rau mob plab hnyav hauv cov menyuam yaus.Tsis ntev los no, kev kuaj mob tshwj xeeb ntawm tus kab mob rotavirus tau dhau los los ntawm kev kuaj pom tus kab mob antigen hauv cov quav los ntawm cov txheej txheem immunoassay xws li latex agglutination assay, EIA, thiab lateral flow chromatographic immunoassay.Rotavirus Ag Rapid Test yog ib qho lateral flow chromatographic immunoassay uas siv ib khub ntawm cov tshuaj tiv thaiv tshwj xeeb txhawm rau txheeb xyuas cov kab mob rotavirus hauv cov quav.Qhov kev sim tuaj yeem ua tiav yam tsis muaj cov cuab yeej kuaj sim, thiab cov txiaj ntsig muaj nyob hauv 15 feeb.

Rotavirus Ag Rapid Test yog lateral flow chromatographic immunoassay.

Test strip muaj xws li:

1) burgundy coloured conjugate ncoo uas muaj monoclonal anti-rotavirus antibody conjugated nrog colloidal kub (anti-rotavirus conjugates) thiab tswj antibody conjugated nrog colloidal kub

2) nitrocellulose membrane strip uas muaj cov kab xeem (T kab) thiab kab tswj (C kab).

T kab yog pre-coated nrog lwm monoclonal anti-rotavirus antibody, thiab C kab yog pre-coated nrog ib tug tswj kab antibody.